Albumin is the most abundant protein found in human plasma. It plays important role as a carrier protein by binding and transporting hormones, cations, fatty acids and medications. Albumin is also responsible for the regulation of the colloidal osmotic pressure of blood. Colloidal osmotic pressure is the pressure required to prevent the flow of blood out of the blood vessels into the surrounding tissue. Albumin is synthesized in the liver and released in the blood to perform these physiological functions. Certain conditions lead to loss of albumin such as liver and kidney disease, burns and adult respiratory distress syndrome (click here to learn more). Under such situations of hypoalbunemia or albumin deficiency the patient is infused with source plasma derived albumin. Albumin is manufactured from the last fraction or Fraction V during the source plasma fractionation procedure (click here to learn more).
- Burn and shock victims
- Adult respiratory distress syndrome
- Hemolytic disease of the newborn